Interaction between iron oxide nanoparticles (Fe3O4 NPs) and human neutrophils: Evidence that Fe3O4 NPs possess some pro-inflammatory activities

A Saafane, D Girard - Chemico-Biological Interactions, 2022 - Elsevier
… This agrees with a recent in vivo study revealing that neutrophils ingesting Fe 3 O 4 @TiO
2 … Also, our results agree with the above in vivo observations reporting that Fe 3 O 4 NPs-…

In vitro inhibition of tumor growth by low-dose iron oxide nanoparticles activating macrophages

L Zhang, S Tan, Y Liu, H Xie, B Luo… - Journal of Biomaterials …, 2019 - journals.sagepub.com
… This study investigated the effects of Fe 3 O 4 magnetic nanoparticles on RAW264.7 cells
proliferation, migration, and inhibition of tumor growth in vitro. Fe 3 O 4 magnetic nanoparticles

In vitro cytotoxicity study of superparamagnetic iron oxide and silica nanoparticles on pneumocyte organelles

A Solorio-Rodríguez, V Escamilla-Rivera… - Toxicology in Vitro, 2021 - Elsevier
… It is important to emphasize that we observed the interaction of NP-loaded vesicles and … In
agreement with our findings, in vivo studies have shown that SiO 2 NP are particularly capable …

[HTML][HTML] The use of iron oxide nanoparticles to reprogram macrophage responses and the immunological tumor microenvironment

V Mulens-Arias, JM Rojas, DF Barber - Frontiers in immunology, 2021 - frontiersin.org
… different cell types, especially their interaction with the macrophages that are involved in their
… and macrophage activation, and to reduce the OVA-expressing CT26 tumor burden in vivo (…

Biological interactions of ferromagnetic iron oxide–carbon nanohybrids with alveolar epithelial cells

S Vercellino, I Kokalari, ML Cantoral, V Petseva… - Biomaterials …, 2022 - pubs.rsc.org
Iron oxide nanoparticles (IONPs) have been largely … @C biological interactions in vitro,
providing them with an in vivo-… a widely employed model of alveolar epithelial cells for a variety of …

The intrinsic biological identities of iron oxide nanoparticles and their coatings: unexplored territory for combinatorial therapies

V Mulens-Arias, JM Rojas, DF Barber - Nanomaterials, 2020 - mdpi.com
… Over the last 20 years, iron oxide nanoparticles (IONPs) have … the complex dynamics of
their interaction with biological systems (… , IONPs also interact with different cell types in vivo, a …

p53 Promotes Ferroptosis in Macrophages Treated with Fe3O4 Nanoparticles

C Wu, Z Shen, Y Lu, F Sun, H Shi - ACS Applied Materials & …, 2022 - ACS Publications
… in vivo, but their cytotoxicity in vivo is not yet apparent. As most of the NPs applied in vivo are
captured and metabolized by macrophages… basis for studying the cytotoxicity of NPs in vivo. …

Modulation of pulmonary toxicity in metabolic syndrome due to variations in iron oxide nanoparticle-biocorona composition

L Xia, S Alqahtani, CR Ferreira, UK Aryal, K Biggs… - Nanomaterials, 2022 - mdpi.com
… and inflammatory responses were evaluated in vitro to determine the contribution of …
within alveolar macrophages demonstrating that they are a primary cell type interacting with …

Plasma protein adsorption on Fe3O4-PEG nanoparticles activates the complement system and induces an inflammatory response

V Escamilla-Rivera, A Solorio-Rodriguez… - International journal …, 2019 - Taylor & Francis
… Understanding of iron oxide nanoparticles (IONP) interaction … In this study, we investigated
whether the interaction of … response in an in vivo and in vitro model. Despite the fact that PEG …

Environmentally relevant iron oxide nanoparticles produce limited acute pulmonary effects in rats at realistic exposure levels

C Guo, RJM Weber, A Buckley, J Mazzolini… - International Journal of …, 2021 - mdpi.com
vitro and in vivo in the alveolar macrophage population, but not in the epithelial cells of the
alveolar … relate more specifically to the interactions between particles and respiratory tissues. …